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One or more keywords matched the following properties of Xie, Huan
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overview I have a strong background in drug characterization, formulation, novel delivery systems, pharmacokinetics and nanotechnology, with a focus on preclinical drug development. I have the specific training, expertise, leadership, and motivation to conduct the proposed project. Currently, I serve as the Founding Director of the Institute of Drug Discovery and Development (iD3) at TSU, which is an NCI-designated subcontractor to provide service for investigators cross the United States. I am the PI and Director of the Research Centers in Minority Institutions (RCMI) Center for Biomedical and Minority Health Research (CBMHR) supported by NIMHD. I am also co-Director of the Gulf Coast Consortia (GCC) Center for Comprehensive PK/PD and Formulation (CCPF) which is funded by the Cancer Prevention & Research Institute of Texas, known as CPRIT. I had four years of industrial experience as Senior Research Scientist working on silica/gold nanoshells for photothermal ablation cancer therapy, which has been used in several cancer clinical trials. Since joining Texas Southern University in 2008, I have successfully completed over 60 research projects, taught over 1000 Pharm.D. students, and personally mentored 10 research scientists/postdoctoral fellows, and over 30 Ph.D., Pharm.D., and undergraduate students, most of whom were underrepresented minorities (URM). I have served as Program Director of the Graduate Program of Pharmaceutical Sciences (GPPS) since 2020, focusing on mentoring the next generation of URM scientists in the field of Pharmaceutics. These trainees were highly sought by employers, such as the FDA, drug companies, hospitals, and academia. As PI or co-Investigator on several NIH- and private agency-funded grants, I laid the groundwork for the proposed research by developing novel analytical methods, advanced drug formulations, and delivery systems and establishing pharmacokinetic and biodistribution profiles. In addition, I successfully administered funded projects (e.g. staffing, research progress, budget, etc.), collaborated with other researchers from institutions across the U.S., generated patents, and produced peer-reviewed publications from these projects (see select list below). These previous experiences made me aware of the importance of frequent communication among project members, and of constructing a realistic program plan, research design, timeline, and budget. Affiliation • American Association of Pharmaceutical Scientists (AAPS) • American Association for Cancer Research (AACR) • American Association of Colleges of Pharmacy (AACP) • Rho Chi Honor Society in Pharmacy (former student advisor) • Gulf Coast Consortia (GCC) • American Chemical Society (ACS) • Phi Lambda Upsilon Honorary Chemical Society
One or more keywords matched the following items that are connected to Xie, Huan
Item TypeName
Academic Article A simple, sensitive and reliable LC-MS/MS method for the determination of 7-bromo-5-chloroquinolin-8-ol (CLBQ14), a potent and selective inhibitor of methionine aminopeptidases: Application to pharmacokinetic studies.
Academic Article Pre-Clinical Pharmacokinetics, Tissue Distribution and Physicochemical Studies of CLBQ14, a Novel Methionine Aminopeptidase Inhibitor for the Treatment of Infectious Diseases.
Concept Ethanol
Concept Aminopyridines
Concept Quaternary Ammonium Compounds
Concept Anilides
Concept Antifungal Agents
Concept Antineoplastic Agents
Concept Catalase
Concept Chloroquinolinols
Concept Chromans
Concept Copper Radioisotopes
Concept Curcumin
Concept Cyclohexanes
Concept Delayed-Action Preparations
Concept Dithionitrobenzoic Acid
Concept Doxorubicin
Concept Drug Carriers
Concept Drug Stability
Concept Enzyme Inhibitors
Concept Enzymes, Immobilized
Concept Fluorescamine
Concept Glucuronidase
Concept Glutathione
Concept Gold
Concept Hydrazones
Concept Ligands
Concept Liposomes
Concept Metals
Concept Mycophenolic Acid
Concept Neoplasm Proteins
Concept Oligopeptides
Concept Peptides
Concept Peptides, Cyclic
Concept Polyethylene Glycols
Concept Polyglycolic Acid
Concept Polylysine
Concept Polysorbates
Concept Proline
Concept Pyrrolidinones
Concept Receptors, Androgen
Concept Rhodamines
Concept Serum Albumin, Bovine
Concept Solvents
Concept Succinimides
Concept Sulfhydryl Compounds
Concept Vitamin E
Concept 2,2'-Dipyridyl
Concept Oxyquinoline
Concept Gene Products, tat
Concept Drug Delivery Systems
Concept Octoxynol
Concept Itraconazole
Concept Gold Colloid
Concept Radiopharmaceuticals
Concept Lactic Acid
Concept Pharmaceutical Solutions
Concept Glucuronides
Concept Tacrolimus Binding Proteins
Concept Integrin alphaVbeta3
Concept Macromolecular Substances
Concept Inhibitor of Differentiation Proteins
Concept HSP27 Heat-Shock Proteins
Concept Coordination Complexes
Academic Article Development and validation of a sensitive LC/MS/MS method for the determination of ?-tocotrienol in rat plasma: application to pharmacokinetic studies.
Academic Article Development of PLGA-based itraconazole injectable nanospheres for sustained release.
Academic Article Pharmacokinetic behaviors of soft nanoparticulate formulations of chemotherapeutics.
Academic Article In vitro dissolution considerations associated with nano drug delivery systems.
Academic Article Surfactant Mediated Accelerated and Discriminatory In Vitro Drug Release Method for PLGA Nanoparticles of Poorly Water-Soluble Drug.
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  • Designing
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